Thorgeirsson received his PhD (Physical Chemistry) in 1992 from the University of California Santa Cruz. He did postdoctoral work at Department of Chemistry, University of California Berkeley, and Division of Structural Biology at the Lawrence Berkeley National Laboratory. In 1997 he joined deCODE genetics and has since worked on various deCODE genetics research projects, both projects of general interest such as the generation of genetic maps and individual projects aiming to identify genes contributing to complex disorders, CNS disorders in particular. He has led the addiction research program at deCODE and also works on the genetics of schizophrenia, bipolar disorder, depression, anxiety, personality, and chronic pain.
1. Thorgeirsson TE, et al.. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 2008. 3;452(7187):638-42.
2. Stefansson H., et al. Common variants conferring risk of schizophrenia. Nature 2009. 460(7256):744-7.
3. Thorgeirsson TE, et al. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet 2010. 42(5):448-53.
4. Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet. 2011 Sep 18;43(10):977-8.
5. Power RA, et al. Polygenic risk scores for schizophrenia and bipolar disorder predict creativity. Nat Neurosci. 2015 Jul;18(7):953-5.
6. Bjornsdottir G, et al. Sequence variant at 8q24.21 associates with sciatica caused by lumbar disc herniation. Nat Commun. 2017 Feb 22;8:14265.
7. Reginsson GW, et al. Polygenic risk scores for schizophrenia and bipolar disorder associate with addiction. Addict Biol. 2018 Jan;23(1):485-492.
8. Wray N, et. al. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nat Genet 2018. 50(5):668-81.
9. Kong A, et al. The nature of nurture: Effects of parental genotypes. Science. 2018 Jan 26;359(6374):424-428.
10. GSCAN consortium. Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. Nat Genet. 2018. in press.